This application lowers the color temperature of your computer screen after sundown. Lower temperature = less blue.
I try to avoid fluorescent lights at night. This is along those lines.
Thanks to Peter McLeod.
This application lowers the color temperature of your computer screen after sundown. Lower temperature = less blue.
I try to avoid fluorescent lights at night. This is along those lines.
Thanks to Peter McLeod.
Medical ghostwriting is plagiarism with a bullet: not only do med-school profs get the benefits of a published article they didn’t write, that published article — written by a drug-company hack — is inevitably misleading, causing doctors to prescribe a drug that is worse than they think. (Which is the whole point.) Patients who take the drug are the big losers.
This sort of thing is so patently awful — especially the harm done to millions of sick innocent people — that you’d think everyone finds it repulsive. Quite the opposite. Living breathing med school professors, such as New York University professor Lila Nachtigall, have trouble seeing what’s so bad about it. The practice appears so common that Senator Grassley asked the ten top medical schools, such as Harvard, Johns Hopkins, and UCSF, to say their policies about it. He’s asking them: Do you consider plagiarism wrong? Except it’s much worse than plagiarism. Although several say on their websites that it’s wrong, Duke University says that “Severe and/or repeated offenses will result in formal disciplinary action”– in other words, non-severe examples are okay! At least the first time. “Formal disciplinary action” can be as mild as a letter. At Duke, at least, they have trouble grasping how awful it is.
This might seem to have nothing in common with self-experimentation. Self-experimentation can be done by anyone, costs nothing, and is a way to figure out helpful truths; whereas almost no one can get a drug company to write a paper for them (you need to be at a top medical school), drugs are a hundred-billion-dollar/year business, and this sort of ghost-writing is done to hide helpful truths. In a better world, they really would be worlds apart. But you are reading this not because I did self-experimentation but because I did self-experimentation that found out something useful and surprising — the Shangri-La Diet and new ideas about sleep and mood. A big reason it did so was that the experts in those fields — such as the relevant med school professorsĂ‚ — were utterly and completely asleep, so to speak. They were incapable of making significant progress. Extreme careerism — putting one’s career ahead of everything else — is no doubt one reason. They could have done what I did. Fat weight-control profs could have tested different diets on themselves, for example. But doing good research would be harmful to their career (e.g., not enough publications), so they don’t do it. Medical ghostwriting helps their career, so they take advantage of it. So what if millions of sick people are harmed by these decisions.
My surprisingly-productive self-experimentation and the staggeringly careerist decisions of med school profs are two sides of one coin: the profound stagnation in health care. The complete inability of those in charge to innovate effectively. Drug companies are businesses that make drugs. They are not going to explore non-drug low-cost solutions, such as those I explored. Nothing, however, prevents med school profs from doing so — at least, nothing except their extreme careerism. My self-experimentation shows what could have been done. It shows that the health questions we face (e.g., how to lose weight) have solutions much better than a new drug. The widespread practice of medical ghostwriting is one indication why those solutions haven’t been found. Failure to find new solutions means problems have stacked up unsolved, getting worse and worse (the obesity epidemic, the allergy epidemic, etc.). It’s usually called a healthcare crisis — but it’s really a health crisis.
A year and a half ago, Charles Richardson was given antibiotics for an ulcer. He writes:
When they put me on the course of antibiotics for the ulcer, my digestion absolutely went south. Stools became runny and smelly and irregularly timed. Even though I took a lot of supposedly high-end probiotic capsules, that went on for months after the antibiotics.
Six months ago — a year after the antibiotics — he started drinking kefir because of this blog. “After about a month [of kefir], I was back to normal,” he writes. He got the starter culture from kefirlady.com (where they cost $20 cash).
More recently he has seen further improvements:
I had a number of food allergies, particularly wheat. If I ate any wheat, I’d get hemorrhoids immediately, and sometimes what looked like a herpes outbreak.
I’ve had that for 30 years or so, but it appears to have gone away in the last month. I had to eat some pasta at a formal dinner, and was expecting a reaction, but had none. I was shocked. I also have a similar reaction to chicken, and had the some non-experience with some of that recently.
I don’t know to what I can attribute that change. The kefir could have helped,and possibly the Vitamin D [about 4000 units/day]. I also started take an amino acid dipeptide of L-glutamine/L-alanine. https://www.kyowa-usa.com/brands/sustamine.html) [about 10 g/day]
This is informative for several reasons.
First, the bad effects of the antibiotics lasted a really long time (a year). This indicates how bacteria-poor a normal American diet is. Richardson probably ate healthier than normal given that he once owned a health-food store.
Second, expensive probiotics didn’t help. This is why I make kombucha and yogurt, to have more quality control. And yogurt is surely closer to what our ancient ancestors ate to get bacteria than probiotic capsules.
Third, the kefir took about a month to solve the problem. This gives an idea of the time it takes to repopulate your intestine with bacteria. And thus how long you should try this or that solution before giving up.
In an earlier post I linked to a poll at This Is MS that asked if there is a correlation between getting red in the face after exercise and having multiple sclerosis. Such a correlation would support Paulo Zamboni’s idea that MS is due to poor blood circulation in the brain.
A poll at This Is MS is likely to be answered by people who have MS. Nancy Lebovitz realized she could help get answers from people who don’t have MS — crucial to learning if there is a correlation — by posting the poll on her LiveJournal page.
The two polls taken together show a strong correlation. Out of 40 people with MS, 72% get red-faced. Out of 27 people without MS, 22% get red-faced. Thanks, Nancy.
Elizabeth Kolbert, the New Yorker staff writer, did not know that Phil Jones, a climate-change scientist, manuevered to keep hidden information that disagreed with his conclusions. Here is what one of the damning emails gathered from the University of East Anglia’s Climate Research Unit said:
From Phil Jones [head of the Climate Research Unit]. To: Michael Mann. Date: May 29, 2008
“Can you delete any emails you may have had with Keith re AR4? Keith will do likewise.”
To keep them from being exposed via a Freedom of Information law. Robin Hanson and Tyler Cowen think this is no big deal. I disagree. Yes, I said before this happened that the consensus was likely to appear stronger than it is and that bloggers were a powerful force toward truth — both of which this episode merely supports rather than reveals. And, yeah, it’s just email; the really damning info is the tree-ring data reanalyzed by Stephen McIntyre.
The reason I think this is important is two-fold. First, this is not a smoking gun. Global warming does not equal the honesty of Phil Jones. But it is a powerful piece of evidence that climate skeptics can use to convince anyone that the consensus isn’t as consensus-y as it appears. Second, it exposes what Kevin Trenberth (a proponent of man-made global warming) really thinks. This is something that few knew until now. Here is what he really thinks:
The fact is that we can’t account for the lack of warming at the moment and it is a travesty that we can’t. The CERES data published in the August BAMS 09 supplement on 2008 shows there should be even more warming: but the data are surely wrong. Our observing system is inadequate.
The data are surely wrong. Trenberth, being human, is going to put the best possible spin on things, the spin most consistent with what he has said many times . . . and this is what he comes up with. Support for the idea of global warming is entirely based on climate models. No one has created a mini-Earth and done experiments. If the data and models don’t agree, there is no reason to believe the models. And if you don’t believe the models you have no reason to believe in global warming. Is Trenberth an ignoramus whose honest assessment of the situation (the models and the data profoundly disagree) should be ignored? Of course not. He doesn’t draw the obvious conclusion (the models are wrong) but nothing prevents the rest of us from doing so.
Just to be clear: I completely agree with Robin’s larger point that this sort of thing supports prediction markets. And I think reduced reliance on fossil fuel would be a very good thing.
Most people look at my research and see self-experimentation. I see a new way to understand diseases of wealth (often called diseases of civilization). We get sick because we live differently than our long-ago ancestors. Self-experimentation is powerful enough to sort through the thousands of differences between modern life and long-ago life to find those that matter.
In an experiment about the value of circadian rhythms to chipmunks, Patricia DeCoursey, a professor of biology at the University of South Carolina, found that their value was revealed by stress created by wealth:
In one experiment she discovered that chipmunks without an internal circadian clock appear quite normal at first. They can survive in optimal conditions; during the first year after their internal clocks were disabled, “predation by weasels was minimal,” she says. But then the chipmunk population increased strikingly due to two successive years of abundant acorn crops in the forest. The weasel population also increased, following the growth of the chipmunk population. Under these more crowded conditions, the restless nighttime movements of the arrhythmic chipmunks in their burrows clued the weasels in to their locations, and predation increased dramatically. The weasels killed all but four of the 100 chipmunks in this population.
When Paulo Zamboni’s wife came down with MS (multiple sclerosis), he was in an unusual position: He was a professor of medicine. Not only did he have technical expertise, he was going to care far more than than most MS researchers about finding a cure. (Likewise, when I suffered from early awakening, I had both technical expertise and cared more about finding a solution than any sleep researcher.)
Using ultrasound to examine the vessels leading in and out of the brain, Dr. Zamboni made a startling find: In more than 90 per cent of people with multiple sclerosis, including his spouse, the veins draining blood from the brain were malformed or blocked. In people without MS, they were not. [emphasis added] . . . More striking still was that, when Dr. Zamboni performed a simple operation to unclog veins and get blood flowing normally again, many of the symptoms of MS disappeared. . . . His wife, who had the surgery three years ago, has not had an attack since. . .
The initial studies done in Italy were small but the outcomes were dramatic. In a group of 65 patients with relapsing-remitting MS (the most common form) who underwent surgery, the number of active lesions in the brain fell sharply, to 12 per cent from 50 per cent; in the two years after surgery, 73 per cent of patients had no symptoms.
Clearly Dr. Zamboni has discovered something very important. Perhaps no true health breakthrough would be complete without appalling responses from powerful people within the biomedical establishment. The American MS society issued a comment on these findings that the rest of us can marvel at. According to them, people with MS should not get tested for malformed or blocked veins!
Q: I have MS. Should I be tested for signs of CCSVI?
A: No, unless you are involved in a research study exploring this phenomenon, since at this time there is no proven therapy to resolve any abnormalities that might be observed, and it is still not clear whether relieving venous obstructions would be beneficial.
Persons with MS cannot be trusted with the dangerous knowledge of whether or not their veins are malformed or blocked! The Chairman of the Board of the National MS society is Thomas R. Kuhn. The President is Joyce M. Nelson. I would love to know how they justify this position. I wrote to the National MS society asking how Kuhn justifies this. The Canadian MS society is far less negative, perhaps due to public pressure.
Over at This Is MS, the National MS position is derided. Someone has made the shrewd observation that if there is something to Zamboni’s idea, persons with MS should get a red head after exercise more often than persons without MS and is collecting data to see if this is true. There seems to be something to it.
Not only is this a wonderful discovery but it is wonderful how the National MS Society can simply be ignored. There are now much better sources of information.
Thanks to Anne Weiss, Charles Richardson, and James Andwartha.
This 2008 study done at Duke University found that small amounts of Splenda — similar to what a person might consume — reduced “beneficial bacteria” in the guts of rats. The effect was very large (reduction by about 50% in 12 weeks) and occurred even at the lowest dose, which was lower than what the FDA allows. Most ominous of all, the effect had not levelled off after 12 weeks. The number of bacteria was still going down.
Within a day two different people told me (in the comments to this blog) about this study, which was published a year ago. A press release about the study. The research was funded by the Sugar Association. Someone recently told me that the only way doctors learn about bad side effects of this or that drug is when drug reps selling competing drugs tell them. While reading about this I came across this chilling comment:
Excitotoxins are implicated in Parkinson’s as well… makes you wonder about Michael J. Fox – his time as Diet Pepsi’s spokesperson and his admitted addiction to the stuff for decades. I remember seeing an interview with him. His head was shaking from the Parkinson’s and his Diet Pepsi was right next to him.
One of the authors of the Duke study is a professor of psychiatry, Susan Schiffman. An earlier study of hers had pro-Splenda results.
More The makers of Splenda issued a press release that could not be less convincing. The study, it says, has “major deficiencies” that include “a lack of appropriate control groups necessary for understanding results.” No statement of what those control groups are. The press release also claims that because the investigators did not measure food and water intake, the results are meaningless! The idiotic press release is made even more curious by the statement quoted in the comments below, that “Drs. Abou-Donia and Schiffman admitted that some of the results recorded in their report submitted to the court were not actually observed or were based on experiments that had not been conducted.” But these, too, are not described. Which means to me that the details are not on Splenda’s side, or they would have been presented. It sounds like really bad news for Splenda.
A study using a rat model of acid reflux found that the problem is inflammation caused by the immune system, not stomach acid damaging tissue, as had previously been thought.
[The] study in rats showed that gastroesophageal refluxĂ‚ causes tissue in the esophagus to release immune chemicals called cytokines, which attract inflammatory cells. These cause the heartburn and chest pain that make GERD [gastroesophageal reflux disease] so distressing.“Currently, we treat GERD by giving medications to prevent the stomach from making acid,” said Dr. Rhonda Souza, who led the study published in the November issue of Gastroenterology.
“But if GERD is really an immune-mediated injury, maybe we should create medications that would prevent these cytokines from attracting inflammatory cells to the esophagus and starting the injury in the first place.
Months ago I posted about a friend of mine whose acid reflux was cured by drinking kombucha. The implication of that case and the rat study is that acid reflux is caused by an over-active immune system. Perhaps stomach acid often gets into the esophagus. Only if your immune system is under-stimulated does this cause trouble.
Acid reflux is very common. According to the article, 20% of Americans “have it regularly”. All this supports my view that we need plenty of bacteria in our diet to be healthy, that few Americans get enough bacteria in their diet, and that the deficiency causes all sorts of digestive and immune problems.