A Clue About How To Sleep Better

A few nights ago I slept surprisingly well: I woke up feeling more rested than usual. Each morning I judge how rested I feel on a scale from 0 to 100 where 0 = as if I hadn’t slept and 100 = completely drained of tiredness. I got scores of 100 after standing 9 or 10 hours during the day. That showed what was possible but that much standing was unsustainable. Without extreme standing, 99 has seemed to be the maximum.

A few nights ago, I did better. The ratings for that night and the preceding four nights were: 98.9, 98.8, 99, 98.8, 99.2. Doesn’t look like much, but actually the improvement was so clearly unusual I didn’t need records to notice it. If I gave the scores for the preceding 100 nights you’d see it was rare to score above 99. Moreover, I was keeping the amount of animal fat I ate constant, unlike previous nights with scores above 99. The difference between 98.8 and 99.2 is easy to notice. Think of the difference between 12 and 8.

What had improved my sleep? I could think of four unusual things about the preceding day:

1. Several cloves of garlic in the pork-belly soup I ate for lunch. I’d never before added any garlic.

2. I began using f.lux, which reduced the color temperature of my computer screen after sunsight.

3. I’d played Dance Dance Revolution (on the Wii) for 10 minutes at 8 pm. Usually I do it in the morning (much longer, 30-50 minutes).

4. More bike riding than usual (including two long stretches that added up to 66 minutes).

All four seemed unlikely. 1. Who’d heard of garlic improving sleep? Not me. 2. Laptop screens are quite dim compared to sunlight. 3. The amount of exercise was small. I’d played Wii Tennis for longer periods in the evening without noticing any change. DDR in the morning hadn’t made an obvious difference. 4. I’d ridden my bike for 50-odd minutes at a stretch without noticing better sleep. This was only slightly more.

Now I am testing these possibilities. If you have any idea which it is — perhaps it is none of them — please comment.

A Disease of Wealth in Squirrels

Most people look at my research and see self-experimentation. I see a new way to understand diseases of wealth (often called diseases of civilization). We get sick because we live differently than our long-ago ancestors. Self-experimentation is powerful enough to sort through the thousands of differences between modern life and long-ago life to find those that matter.

In an experiment about the value of circadian rhythms to chipmunks, Patricia DeCoursey, a professor of biology at the University of South Carolina, found that their value was revealed by stress created by wealth:

In one experiment she discovered that chipmunks without an internal circadian clock appear quite normal at first. They can survive in optimal conditions; during the first year after their internal clocks were disabled, “predation by weasels was minimal,” she says. But then the chipmunk population increased strikingly due to two successive years of abundant acorn crops in the forest. The weasel population also increased, following the growth of the chipmunk population. Under these more crowded conditions, the restless nighttime movements of the arrhythmic chipmunks in their burrows clued the weasels in to their locations, and predation increased dramatically. The weasels killed all but four of the 100 chipmunks in this population.

More Animal Fat, Better Sleep

After I wrote about eating a lot of pork fat and sleeping better, David Shackelford commented that he had had a similar experience: After he started eating much more animal fat and meat, he too slept better. (He posted about this before he read my post.) I asked him for details. He answered:

About three weeks ago, I started a carnivorous diet. I did this primarily for its supposed benefit to insulin sensitivity, energy levels, and general health, and also because I wanted to see if it was really possible to thrive on nothing but meat.

Immediately after starting, I noticed that I was sleeping easier, longer, and deeper, and having more vivid dreams than usual. I’ve had a hard time falling asleep for my entire life, usually taking 45 minutes to two hours after going to bed, and occasionally not being able to sleep at all, so this was a very pleasant surprise.

At first I thought that this was due to standing on one foot, which I had started a few days prior, but I stopped one-foot-standing and the effect persisted. The all-meat diet has been pretty great all around-food is delicious, I’ve got a ton of energy, and I’m rarely hungry-but the sleep has been the best part.

Me
21 years old (senior in college)
130-ish lbs
5’4″
12-15% body fat
Moderately active, fairly good shape.

My diet
-Breakfast of 3-4 egg omelette, with 1-2 oz cheese and occasionally bacon.
-Lunch: chicken breast, sausage, or eggs.
-Dinner: 1lb+ steak.
-Snacks: nuts and/or cheese.

Approximate macronutrient composition
Before: 50% carbohydrate / 30% protein / 20% fat (at least half unsaturated olive oil)
After: 60-70% fat (all animal fat), 30-40% protein;10% carbohydrates (nuts and the occasional glass of wine, plus trace amounts in sauces and cheeses). Unsure of my caloric intake; I think it varies between 1500 and 2000 a day.

Other
-I cook chicken, beef, and eggs in butter.
-I drink coffee 1-2 times a day, and tea about once a day.
-I take a multivitamin (I don’t know why), 5,000 IU Vitamin D (I live in Oregon, which gets very little sunlight), and 2.5g fish oil (the grain-fed beef I eat has low 3:6 ratios; if I could afford grass-fed, I probably wouldn’t need the fish oil).
-I let the diet go on weekends, for the sake of social life. I probably have 3-5 drinks on Friday and Saturday night, as well as some junk food (pizza/chips/fries). I feel like I don’t sleep quite as well on these days, but there are so many confounding variables (alcohol, staying up later than usual, seeing faces later into the night, sex) that isolating a cause of the difference is tough.

Exercise
-I lift weights for about 30 minutes, twice a week.
-I go out social dancing for about four hours, once to twice a week.
-Sleep does not seem to vary with whether I exercise or not.

He blogs about this at meatsaur.us. His story is more evidence that the animal fat/sleep connection is cause and effect (animal fat –> better sleep), and suggests that the effect is not limited to me.

My self-experiment about this.

Why Are Colds and Flu More Common in Winter?

The effect is so large, so easy to notice, it is enshrined in the word cold. We get far more colds and flu in the winter (“flu season”) than in the summer. In this excellent interview, epidemiologist Thomas Jefferson asks:

Why, for example, do we not get influenza in the summertime?

All of the possible explanations listed in this Wikipedia article assume that it is cold weather that makes flu more common in winter. However, an impressive 1981 study found that flu peaked during the light minimum, not the temperature minimum, contradicting all of these explanations.

My proposed explanation is that flu is less common in the summer because people sleep better during the summer. They sleep better in the summer because they get more morning light. More morning light causes your circadian system to have a greater amplitude, which means you sleep more deeply. Better sleep –> better immune function. When I started to sleep much better, I stopped getting noticeable colds and flu.

When I wrote my paper it was essentially impossible to test my idea. You need to measure a lot of sleep — and sleep scientists, intent on making it hard to do what they do, have made this nearly impossible. Perhaps it will soon be easier. To begin with, to test my idea you’d need to improve sleep somehow. To get more light exposure during winter is easy enough with a light box but measuring quality of sleep is much harder. Maybe FitBit (which will start shipping in a few months) will make this possible. I tried using SleepTracker to measure my sleep but after a few months I gave up. There were four big problems: 1. The interface didn’t work very well. It was often hard to get the data from the device into my computer. 2. The whole thing wasn’t designed to measure sleep, it was designed to wake you at a better time than you would wake up without it. 3. The way it measured sleep was a secret. 4. The output — the measure of sleep — was binary. All you were told was whether movement was above or below some threshold. And I had no idea how that threshold was determined.

Sickness After Starting to Eat Yogurt

A friend writes:

As of today I’m getting over my fourth cold since I began eating lots of yogurt (maybe 1-2 cups a day, homemade), which was roughly in March of this year. So that would be a rate of about a cold every two months. On the one hand that sounds pretty terrible. On the other hand, a couple of things to think about:

1. I used to always get colds and other sicknesses as well. They just seem to be attracted to me. By my intuition, the current rate doesn’t seem particularly unusual, although I never kept track before. If anyone had a cold anywhere around me, invariably I got it. It’s been that way as long as I can remember, especially when I was traveling, as I have been during these last few months.

2. Each of the colds I have had in this last eight month period has been remarkably short. Really remarkable, so I will remark, by way of example, that this cold came out of the blue yesterday evening with a fit of sneezing. I hadn’t felt bad at all earlier in the day although in retrospect it’s possible I was a bit worn down (or maybe not: I took a half-hour swim in the late afternoon and felt pretty good). So I sneezed my way through an evening, nose dripping like a faucet. Before going to sleep I took some sort of medicine for cold symptoms (maybe something made by Bufferin maybe? Night/day something…), and in the morning I took the same thing (day version). During that whole time I was still pretty symptomatic: sneezing, nose dripping etc., but I guess the medicine might have been somewhat useful. Now here it is 2:30 in the afternoon and all of a sudden I realize my nose is dry and I haven’t sneezed for hours. I reckon this is about the end of the cold: less than 24 hours. The other three were like that as well: very quick onset, then disappearing almost before I could have time to realize I had a cold. For me this is particularly noteworthy because in years past I always seemed to get the worst of the colds, going on for days and often progressing into a hacking cough that would linger for weeks.

I suspect if my friend improved his sleep he would get see further improvement of these measures of illness. In this study, the frequency of sickness episodes went down for workers given a probiotic but their duration, when they happened, didn’t change — perhaps because it was nice to be away from work.

After I copy-and-pasted that, I got sick. It wasn’t sickness as most people know it. After an afternoon walk (1 hour) I felt tired; that was the first sign. After dinner, I felt really tired. That was an unmistakable sign. I went to bed early, slept about 8 hours (1-2 hours more than usual) and woke up rested. But an hour later I fell back asleep for 15 minutes. At that point I was sure something was wrong. I had a class that morning starting at 10 am. Should I cancel it? I got much more tired and, about two hours before class, was too tired to get out of bed to turn off the beeping yogurt maker. Okay, I’ll cancel class. I phoned the TA to cancel the class but he couldn’t — he had a bad cold. I phoned a student and she phoned the other students.

An hour later, however, I felt much better. By class time I felt well enough to go to class, although I walked rather than ride my bike. (The student did her best to uncancel the class.) In the afternoon I took a long nap (1.5 hours). The next day I was just barely more tired than usual. Today I feel completely well.

I was sick, yes, but without chills, runny nose, sneezing, sore throat — without any discomfort at all unless feeling tired counts as discomfort. And I felt distinctly more tired than usual for only about a day. I think this is what happens when your immune system works properly. You fight stuff off much faster than the five days or so many people take to get better. Before I figured out how to improve my sleep, I got the usual 4-6 colds per year. After I started to sleep much better, I never got sick in the usual runny-nose way so long as my sleep was good. The current episode is striking to me because I was more sick — that is, more tired — than usual. I do only two things to make my immune system work better: (a) improve my sleep in several ways (eat animal fat, get plenty of morning light, stand on one foot); and (b) eat plenty of fermented foods (mostly yogurt, but also miso, kimchi, natto, and kombucha).

Effect of Animal Fat on Sleep (more)

After the striking correlation I described earlier — I ate lot more animal fat than usual and slept longer and had more energy the next day — I started eating much more of what had produced the correlation: pork belly (which is used to make bacon). I couldn’t get uncured pork belly, so I ate bacon. I usually ate it raw. I tried several brands; the only one I liked was from Fatted Calf ($10/pound).

In Beijing I discovered pork belly for sale in every meat department. It is used to make a dish said to be Chairman Mao’s favorite. I bought a soup cooker, an appliance I haven’t seen in America, which made it easy to cook the pork belly. I seemed to sleep better when I had it for lunch.

Finally I did an experiment. I ate pork belly for lunch some days but not others. I ate the pork belly in miso soup, with vegetables. I always ate a whole package of pork belly, which was about 0.7 lb and perhaps 80% fat, 20% meat. On baseline days I ate my usual diet, which was already high-fat by people’s standards. (For example, I ate a lot of whole milk yogurt, a fair amount of nuts, and ordinary amounts of meat.) I tried to alternate baseline and pork-belly days but this wasn’t always possible.
Here are the results on ratings of how rested I felt when I awoke (100% = completely rested = the most rested I have ever felt, 0% = not rested at all).

The lines were fit separately to each set of points (red line to the red points, etc.). The difference is is very consistent (t = 5). Differences in how long I slept were much less clear. I will discuss them in a separate post.

The fascinating thing about this effect isn’t just how clear it is; it’s also how fast it goes on and off (within a day). With most nutrients you’d never see an effect like this. For example, scurvy takes months to develop and a few weeks to recover from. The omega-3 effects I’ve studied have a fast onset but take days to go away.

Sleep is controlled by the brain, of course. The brain is more than half fat, but determinations of how much fat the brain has have measured structural fat. This effect is so fast, both on and especially off, that it must involve circulating fat. Apparently my brain works better when there is a certain amount of animal fat in my blood. This supports Chairman Mao’s idea that pork belly is “brain food” but is a new idea for American intelligentsia. I think the chance that a nutrient that is good for one part of the body is bad for another part is zero — the same as the chance that the electrical appliances you own work best with widely-different currents. The obvious conclusion suggested by this data is that we need plenty of animal fat to be healthy. The only novel element of these lunches was the animal fat. Miso soup with ordinary meat has no effect on my sleep, as far as I know.

I think the science of nutrition proceeds in four steps, repeated over and over for each necessary nutrient: 1. Figure out that we need it. 2. Determine a way to measure how much of it we need. 3. Figure out the optimal amount. 4. Check your answer. With animal fat, conventional nutrition science hasn’t quite reached Step 1. Before this data, I’d say the clearest evidence that we need animal fat is that fat tastes good and long ago we had very little plant fat so it must have been the benefits of animal fat that produced the fat-tastes-good linkage. But conventional nutrition scientists never think this way — never take what we want to eat as meaning anything. And the mere fact that fat tastes good is no help figuring out how much is best.

This data pushes our knowledge toward Step 2. It doesn’t just suggest we need plenty of animal fat for best health, it also makes two methodological points: 1. Animal fat improves brain function. There may be better measures of the improvement than sleep quality. 2. The timing of the improvement — which as far as I know is unprecedented in the study of nutrition — makes it easy to measure.

Yesterday at a Carrefour I watched a pig being cut up. The butcher cut off the skin (with a thick layer of fat) and tossed it into a section of the display of pork for sale. I could buy the part of the pig I valued most for an incredibly low price (about 25 cents/pound). All other pork cost more. That’s how much Chinese shoppers wanted it. No one rushed to buy the newly-cut piece of skin. It reminded me of New York where I tried to buy food past its expiration date, ordinarily considered worthless.

Who is “Totally Healthy”?

I watched this 60 Minutes piece on swine flu. Of course nothing was said about boosting immunity as a defense. “The best way to reduce your chances of one of those terrible outcomes [hospitalization, death] is to be vaccinated,” said Anne Schuchat, who has a very high position at the Centers for Disease Control and Prevention.

This is just part of a bigger delusion. The story centers on a football player who gets seriously sick after a football game. Schuchat said this:

This is one of the tragic parts of this epidemic. That people who are in the prime of their life, totally healthy, can suddenly become so sick.

Totally healthy. This is the bigger delusion: That the average American who appears healthy is healthy. I believe that practically all Americans have grossly-impaired immunity. Their immune systems work much worse than they could. The poor performance is due to suboptimal sleep and far too little bacteria in their diet. The football player was near death because he had two out-of-control infections. That’s how poorly his immune system was working. And a top CDC official called him “totally healthy”! Apparently she has no idea that people’s immune systems can vary in how well they work. This is even worse than the UCLA medical school prof specializing in infectious disease who also failed to understand this. Schuchat is one of the top public health officials in America! Public health is about prevention. According to Wikipedia, Schuchat “has emphasized prevention of infectious diseases in children.”

Hidden Bonus of the L Prize: Better Sleep, Better Mood

The Department of Energy has a prize, called the L Prize, for a new light bulb that gives off same light as a 60-watt incandescent bulb but uses much less energy. Philips has submitted what it believes will be the winning entry. For the last decade, I’ve tried to avoid fluorescent lights at night. Ordinary fluorescent lamps emit light with far more blue than incandescent lamps and mess up my circadian-timing system. That systems appears insensitive to incandescent light. Squirrels are like me, a study suggests.

Fluorescent lights are close enough to sunlight to affect our circadian system; incandescent lights, being much cooler than the sun, are invisible to it. The timing of exposure matters if it varies from day to day; exposure to fluorescent lights at varying times is like travelling back and forth across time zones. Everybody grasps that travelling across time zones makes it hard to sleep at the right time; what is less understood is that time-zone-crossing travel affects the depth of sleep because it reduces the amplitude of the circadian oscillation. If you are exposed to fluorescent lights at night now and then, you will sleep less deeply. So I try hard to avoid fluorescent lights at night. I avoid supermarkets and subways, for example.

I discovered all this when I discovered the effects of morning faces on my mood. After I travelled back and forth across time zones, the effect took three weeks to fully return. Nothing else had changed. I conclude that it took three weeks in the same place for my circadian oscillator to return to maximum amplitude. And one evening in which I was exposed to an hour of fluorescent light was enough to get rid of the faces effect for a few weeks. The ubiquity of fluorescent lighting has made it hard to study this effect in other people.

Sleep and Standing on One Foot

Someone read this blog and wrote this:

The one that was most interesting to me was “standing on one foot”,
because I’ve definitely felt a difference in sleep after doing lots of
work. Â (I used to sleep really well when I did a 54-mile commute on my
bike.) Â Maybe standing on one foot (knee bent) until failure causes the
muscles to send similar chemical signals to intense exercise which are
picked up elsewhere? Â Whatever, it was free, easy, and safe, so I tried
it. Â You can’t do a double-blind experiment on yourself, of course, but
at least some of the time when I’ve tried it I definitely felt as
though I slept more soundly when I got up the next day.

I still do this. Lately I have been varying the dose — how many times I stand on one leg. So far three (e.g., right leg, left leg, right leg) produces slightly worse sleep than four (right leg, left leg, right leg, left leg). If I eat plenty of meat, my legs get stronger and stronger; if I eat little meat, they don’t.