Saturated Fat and Heart Attacks

After I discovered that butter made me faster at arithmetic, I started eating half a stick (66 g) of butter per day. After a talk about it, a cardiologist in the audience said I was killing myself. I said that the evidence that butter improved my brain function was much clearer than the evidence that butter causes heart disease. The cardiologist couldn’t debate this; he seemed to have no idea of the evidence.

Shortly before I discovered the butter/arithmetic connection, I had a heart scan (a tomographic x-ray) from which is computed an Agaston score, a measure of calcification of your blood vessels. The Agaston score is a good predictor of whether you will have a heart attack. The higher your score, the greater the probability. My score put me close to the median for my age. A year later — after eating lots of butter every day during that year — I got a second scan. Most people get about 25% worse each year. My second scan showed regression (= improvement). It was 40% better (less) than expected (a 25% increase). A big increase in butter consumption was the only aspect of my diet that I consciously changed between Scan 1 and Scan 2.

The improvement I observed, however surprising, was consistent with a 2004 study that measured narrowing of the arteries as a function of diet. About 200 women were studied for three years. There were three main findings. 1. The more saturated fat, the less narrowing. Women in the highest quartile of saturated fat intake didn’t have, on average, any narrowing. 2. The more polyunsaturated fat, the more narrowing. 3. The more carbohydrate, the more narrowing. Of all the nutrients examined, only saturated fat clearly reduced narrowing. Exactly the opposite of what we’ve been told.

As this article explains, the original idea that fat causes heart disease came from Ancel Keys, who omitted most of the available data from his data set. When all the data were considered, there was no connection between fat intake and heart disease. There has never been convincing evidence that saturated fat causes heart disease, but somehow this hasn’t stopped the vast majority of doctors and nutrition experts from repeating what they’ve been told.

Short-Term Effects of Fat, Protein and Carbohydrate on Cognition: Fat Best

A German study published in 2001 measured the effect of starkly different breakfasts (all fat, all protein, or all carbohydrate) on cognition during the next hours. Participants (17 men in their 20s) ate the same packaged dinner at home and next morning came to the lab and ate different breakfasts. All of the breakfasts were “cream-like” and all contained 400 calories. The design was relatively sophisticated. Practice effects were reduced by giving considerable practice with the tests before the main measurements began. Brain tests included a simple reaction time task, a choice reaction time task, and a “combi-test” in which the subject does two things at once that provides six measures of performance. One set of tests took 15 minutes. The tests were done once/hour for 3 hours after the breakfast.

The simple reaction time test showed no difference between the breakfasts. The choice reaction time test and the combi-test did show differences: The all-fat breakfast was better. The improvement produced by the fat breakfast compared to the other two breakfasts was clearest about two hours after the breakfast.

EMG (brainwave) measurements showed no differences between the breakfasts.

These results agreed with previous work.

Cunliffe et al. (1997) reported that a pure fat meal did not increase reaction times in contrast to carbohydrate ingestion when measured hourly for 4 h after the meal. In our study, fat ingestion even improved reaction times compared with baseline. Our subjects scored best for all tasks of the combi-test after the fat meal. This finding is in line with the higher accuracy of a focused attention task after a high-fat meal compared with a low-fat meal reported by others (Smith et al. 1994).

The “fat” breakfast in this study was 25% soybean oil (high in omega-6), 25% palm oil (high in saturated fats) and 50% cream (high in saturated fats). I have not compared omega-6 to nothing but I suspect it would produce worse results, given that olive oil appears worse than nothing. So I suspect that the improvement due to fat was due to the palm oil and cream. I concluded, based on evidence that I and others collected, that butter (high in saturated fats) improves arithmetic speed. I usually ate 30 g (= 2 tablespoons = 270 calories) of butter twice/day. Close to the dosage of this experiment. The timing of the effects I saw (sharp improvement from one day to the next) is consistent with a change that happens within 2 hours.

These results, which I didn’t know about until recently, support my earlier conclusions about butter. My measurements cost almost nothing whereas this experiment must have cost thousands of dollars ($400/subject?) plus hundreds of hours of researcher time. Maybe I should compare cream and butter. Cream has advantages. Mark Frauenfelder suggested using cream to make yogurt. Superfood!

A more recent study found saturated fat consumption correlated with cognitive decline. It was a survey, however, with many differences between the groups being compared. I trust experimental evidence much more than survey evidence.

Secrets of a Long Life: Butter, Pork Belly, No Medicine

The New York Times recently ran a story about a 107-year-old woman named Juliana Koo, who lives in New York City. Her longevity secrets are remarkably close to what I say on this blog:

“Somebody asked her the secret of long life,” said Ying-Ying Yuan, a step-granddaughter of Mrs. Koo. “She said, ‘No exercise, eat as much butter as you like and never look backwards.’”

Shirley Young said her mother also likes pork bellies, “especially the hot part, but she doesn’t overdo anything.”

“And she doesn’t take any medicine,” she said. “When doctors give her medicine, she usually hides it, or when she takes something, she takes half a pill. People keep on giving her Chinese herbs, things like that. She never takes them.”

More About Pork Fat and Sleep

One day in 2009, I ate a large amount of pork belly (very high in fat — pork belly is the cut used to make bacon). That night I slept an unusually long time. The next day I had more energy than usual. This led me to do an experiment in which I ate a pork belly meal (with lots of pork belly, about 250 g) on some days but not others. I compared my sleep after the two sorts of days. I kept constant the number of one-legged stands I did each day because that has an effect. During the first half of the experiment I kept this constant at 4; during the second half, at 2. I originally posted the results only from the first half.

Now I’ve analyzed the results from both halves. Here are ratings of how rested I felt when I woke up, on a scale where 0 = 0% = not rested at all and 100 = 100% = completely rested.

The two halves were essentially the same: pork belly produced a big improvement. Here are the results for sleep duration.

No clear effect of pork belly in either half of the experiment.

The main thing I learned was that pork fat really helps. The effect is remarkably clear. With micronutrients, such as Vitamin C, the body has considerable storage. It may take months without the nutrient to become noticeably deficient. With omega-3, which is between a micronutrient and a macronutrient, my experiments found that it takes about two days to start to see deficiency. With pork fat there seems to be no storage at all. I needed to eat lots of pork fat every day to get the best sleep. That repletion and depletion are fast made this experiment easy. How curious we are so often told animal fat is bad when an easy experiment shows it is good, at least for me.

Assorted Links

Thanks to David Cramer.

Assorted Links

  • Correlation between fat intake and brain-test scores. “Those women who reported the highest saturated fat intake also had, on average, the worst scores on reasoning and memory tests.”
  • How many iPads does it take to change a textbook market? A perfectly good physics textbook is now available for free download (pdf). The author of the post, a physics professor at William and Mary named Marc Sher, does not understand what’s going on when he refers to “the textbook publishers’ price-gouging monopoly” and their “outrageous practices”. Textbooks cost so much because students can be forced to pay that much. This has nothing to do with publishers, I submit, and everything to do with the power professors have over students. Sher would reply: All the textbooks are expensive. And I say: So what? If students could choose not to buy $200 textbooks, none would be sold. Zero. And future years would see no more $200 textbooks.

Thanks to Jonathan Graehl.

An Unbiassed View of What We Should Eat . . . From a Rat

In nature animals must choose a healthy diet based on what tastes good. This doesn’t work for modern humans — lots of people eat poor diets — but why it fails is a mystery. There are many possible reasons. Are the wrong (“unnatural”) foods available (e.g., too much sugar, too little omega-3, not enough fermented food)? Is something besides food causing trouble (e.g., too little exercise, too little attention to food)? Are bad cultural beliefs too powerful (e.g., “low-fat”, desire for thinness)? Is advertising too powerful? Is convenience too powerful? Lab animals are intermediate between animals in nature and modern humans. They are not affected by cultural beliefs, advertising, and convenience (the foods they are offered are equally convenient). Their choice of food may be better than ours.

Nutrition researchers understand the value of studying what lab animals choose to eat. In 1915, the first research paper about “dietary self-selection” was published, followed by hundreds more. The general finding is that in laboratory or research settings, animals choose a relatively healthy diet. There are two variations:

[1.] Cafeteria experiments with chemically defined [= synthesized] diets showed that some of these animals, when offered the separate, purified nutrient components of their usual diet, eat the nutrients in a balance that more or less resynthesizes the original diet and that is often superior to it. [2.] Other animals eat two or more natural foods in proportions that yield a more favorable balance of nutrients than will any one of these foods alone.

Both findings imply that housing an animal in a lab does not destroy the mechanism that tells it what to eat.

Which is why I was fascinated to recently learn what Mr. T (pictured above), the pet rat of Alexandra Harney, the author of The China Price, and her husband, liked to eat. It wasn’t obvious. “We tried so many foods with him and always thought it made a powerful statement that even a wild rat turned his nose up at potato chips,” says Alexandra. “He hated most processed food. He also hated carrots, though.” Here are his top three foods:

  1. pate
  2. salmon sashimi
  3. scrambled eggs

Pate = protein, animal fat, complex flavors (which in nature would have been supplied by microbe-rich, i.e., fermented, food). Salmon sashimi = protein, omega=3. Scrambled eggs = ??

He liked beer in moderation, but not yogurt. “Owners of domestic rats say they love yogurt,” says Alexandra, “but Mr T only liked it briefly and then hated it, even lunging to bite a friend who brought him some. [Curious.] He loved cheese, stored bread for future consumption (but almost never ate it). Loved pesto sauce and coconut.” Note the absence of fruits and vegetables. Alexandra and her husband have no nutritional theories that I am aware of. They did not shape this list to make some point.

For me the message is: Why scrambled eggs? I too like eggs and eat them regularly and cannot explain why.

More Alex Tabarrok’s Thanksgiving post shows the connection between libertarian ideas (economies work better when more choice is allowed) and dietary self-selection.

Assorted Links

  • Lard chic. ““I might have a cold,” she says. “Eat this, then,” I say, proffering a piece of hot toast with a thin, transparent slice of cured pork fat.”
  • Skeptical Science is a blog devoted to rebutting every argument offered by AGW skeptics like me. Bishop Hill points out that after two comments were critical of a post about Antarctic ice, the post was rewritten. Rather than point out the rewriting, replies were added to the critical comments saying that the commenters hadn’t read the post (“read and reread the post above”).
  • Nobel Laureates Behaving Badly. “In his Nobel Prize Lecture of December 12, 1946, Hermann J. Muller argued that the dose–response for radiation-induced germ cell mutations was linear and that there was ‘‘no escape from the conclusion that there is no threshold [below which radiation is harmless]“. However, assessment of correspondence between Muller and Curt Stern 1 month prior to his Nobel Prize Lecture reveals that Muller knew the results and implications of a recently completed study at the University of Rochester under the direction of Stern, which directly contradicted his Nobel Prize Lecture.” This is related to radiation hormesis — the observation that low doses of radiation are beneficial. Airport screening may be making people healthier.
  • Harvard’s “Healthy Eating Plate”. No fermented food, nothing about omega-3 (beyond the recommendation of fish). “Limit butter”. “Stay active” but nothing about sleep.
  • Dangers of compact fluorescent lighting.

Thanks to Steve Hansen and Anne Weiss.

Ancestral Health Symposium: Meat versus Fat

Yesterday I was telling a relative about the Ancestral Health Symposium and I mentioned the emphasis on meat eating — for example, two vendors gave out samples of beef jerky. To most people, I think paleo means eating lots of meat. I told my relative I disagreed with this. I find nothing wonderful about meat protein; I would happily get my protein from plants. I eat meat almost only for the associated fat. Which I can get from butter. A lot of meat I am served, such as in fancy restaurants, strikes me as too low in fat. Yesterday I requested butter at a sushi restaurant. The waitress was unsure if they had some.

Today I see Melissa McEwen said the same thing much better:

It was interesting to observe that [at the Ancestral Health Symposium] among the low-carbers, there seemed to be an epidemic of puffy red skin, particularly in older men. I’m sure the pictures, when they are posted, will make obvious who these people are. The ones who had healthy complexions like the Eades and Nora are those espousing a high-fat diet. It goes very well with some of the anthropological stuff I’ve been working on showing that almost all cultures that eat meaty diets are doing so because they have access to high-fat game.